10 Signs of Perimenopause You Shouldn’t Ignore

Early signs of perimenopause: irregular periods, hot flushes, mood changes. Expert guide from Dr Silas Gimba.

10 Signs of Perimenopause You Shouldn’t Ignore

By Dr Silas Gimba, Consultant Obstetrician & Gynaecologist | BMS/MSCP Accredited Menopause Specialist

If you’re in your 40s and experiencing unexplained changes – irregular periods, sudden heat, mood swings – you might be wondering: “Is this perimenopause?” You’re not alone. Perimenopause, the transition to menopause, can begin up to 10 years before your final period. Yet many women don’t recognise the signs.

In this guide, I’ll explain the 10 most common early signs of perimenopause, why they happen, and when you should seek help.

1. Irregular Periods

This is often the first sign. Your cycles may become shorter, longer, heavier, lighter, or you may skip periods altogether. These changes reflect fluctuating oestrogen and progesterone levels as your ovaries become less predictable.

2. Hot Flushes and Night Sweats

A sudden wave of heat spreading through your chest, neck, and face – sometimes accompanied by sweating, palpitations, and a red flush. Night sweats are hot flushes that occur during sleep and can severely disrupt your rest.

3. Sleep Problems

Difficulty falling asleep, frequent waking, or early morning waking. This may be caused directly by hormonal changes, by night sweats, or by increased anxiety. Poor sleep then worsens other symptoms – creating a vicious cycle.

4. Mood Changes

Anxiety, irritability, low mood, mood swings, and feelings of overwhelm are extremely common in perimenopause. These are directly linked to falling oestrogen levels, which affect serotonin and other neurotransmitters in the brain.

5. Brain Fog and Memory Problems

Difficulty concentrating, forgetting words, losing your train of thought, struggling with tasks that used to be easy. This is one of the most distressing symptoms women report. Oestrogen plays a key role in cognitive function.

6. Fatigue

Not just tiredness – a deep, persistent exhaustion that doesn’t improve with rest. Hormonal changes, poor sleep, and the cumulative effect of other symptoms all contribute.

7. Joint Pain and Muscle Aches

Many women in their 40s develop new joint stiffness or aching – particularly in the hands, wrists, knees, and hips. Oestrogen has anti-inflammatory effects, and its decline can increase joint inflammation and discomfort.

8. Changes in Libido

Reduced sexual desire, vaginal dryness, and discomfort during intercourse are common during perimenopause. These are partly hormonal and partly related to fatigue, mood changes, and body image concerns.

9. Weight Gain

Particularly around the abdomen. Declining oestrogen shifts fat distribution from the hips and thighs to the waist. Metabolic changes also make it harder to maintain your usual weight, even without changes to diet or exercise.

10. Heart Palpitations

Sudden awareness of your heartbeat – racing, skipping, or pounding. While usually harmless, palpitations in perimenopause are linked to oestrogen fluctuations affecting the autonomic nervous system.

When Should You Seek Help?

You should seek professional assessment if your symptoms are affecting your quality of life, work, relationships, or sleep; if you are under 40 (possible premature ovarian insufficiency); if you have very heavy or prolonged bleeding; or if you want to understand your treatment options.

What Can You Do Right Now?

  • Track your symptoms – Download our free Menopause Symptom Tracker
  • See your GP – Armed with your symptom record
  • Consider a specialist consultation – For complex symptoms or personalised treatment

Medical Disclaimer: This article is for general information only. Always consult a qualified healthcare professional. MenoCareHealth is regulated by the CQC. Sources: NICE NG23, British Menopause Society Guidelines.